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Article

Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN.

Journal of biochemistry - 1 Feb 2003

Takahashi Mikiko, Gotoh Yusuke, Isagawa Takayuki, Nishimura Tamako, Goyama Emiko, Kim Hon-Song, Mukai Hideyuki, Ono Yoshitaka

Abstract excerpt

PKNalpha is a fatty acid- and Rho-activated serine/threonine protein kinase having a catalytic domain homologous to members of the protein kinase C family. Recently it was reported that PKNalpha is involved in the p38 mitogen-activated protein kinase (MAPK) signaling pathway. To date, however, how PKNalpha regulates the p38gamma MAPK signaling pathway is unclear. Here we demonstrate that PKNalpha efficiently...

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PMID: 12761180
DOI: 10.1093/jb/mvg022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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