Article
Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta.
The EMBO journal - 15 Dec 1995
Berra E, Díaz-Meco M T, Lozano J, Frutos S, Municio M M, Sánchez P, Sanz L, Moscat J
Abstract excerpt
Protein kinase C zeta (zeta PKC) is critically involved in the control of a number of cell functions, including proliferation and nuclear factor kappa B (NF-kappa B) activation. Previous studies indicate that zeta PKC is an important step downstream of Ras in the mitogenic cascade. The stimulatio...
Topics
- Animals
- Base Sequence
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Line
- Cell Nucleus
- DNA
- Enzyme Activation
- Mitogen-Activated Protein Kinase Kinases
- Mitosis
- Molecular Sequence Data
- Mutation
- NF-kappa B
- Promoter Regions, Genetic
- Protein Kinase C
- Protein Kinases
- Signal Transduction
- Tumor Necrosis Factor-alpha