K-ras mutations in sera of patients with colorectal neoplasias and long-standing inflammatory bowel disease.

doi:10.1080/00365520212505

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Article

K-ras mutations in sera of patients with colorectal neoplasias and long-standing inflammatory bowel disease.

Scandinavian journal of gastroenterology - 1 Jun 2002

Borchers R, Heinzlmann M, Zahn R, Witter K, Martin K, Loeschke K, Folwaczny C

Abstract excerpt

BACKGROUND: About 50% of colorectal carcinomas and adenomas display K-ras mutations, which have also been described in stool or colonic lavage fluid. Moreover, the presence of K-ras mutations in plasma samples originating from patients with colorectal cancer has been reported recently. METHODS: DNA was extracted from sera of 16 patients with colorectal carcinomas, 6 with large adenomas, 3 with Crohn disease and 4...

Topics

Adenocarcinoma
Adult
Aged
Aged, 80 and over
Base Sequence
Biomarkers, Tumor
Case-Control Studies
Cohort Studies
Colorectal Neoplasms
DNA Mutational Analysis
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, ras

Genetic Predisposition to Disease

Humans

Inflammatory Bowel Diseases

Male

Middle Aged

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 12126252
DOI: 10.1080/00365520212505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12126252-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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