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Article

K-ras mutations and p53 alterations in neoplastic and nonneoplastic lesions associated with longstanding ulcerative colitis.

The American journal of pathology - 1 Apr 1994

Chaubert P, Benhattar J, Saraga E, Costa J

Abstract excerpt

We have analyzed K-ras mutations and p53 alterations in 39 tumor and nontumor samples taken from nine patients with longstanding ulcerative colitis and colorectal carcinoma. Two of nine invasive carcinomas contained a K-ras mutation. By a combination of immunohistochemistry and single-strand conf...

Topics

Adult
Aged
Base Sequence
Carcinoma
Colitis, Ulcerative
Colorectal Neoplasms
Female
Humans
Immunoenzyme Techniques
Male
Middle Aged
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Oncogene Protein p21(ras)

Polymerase Chain Reaction

Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 8160776
PMCID: PMC1887244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8160776-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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K-ras mutations and p53 alterations in neoplastic and nonneoplastic lesions associated with longstanding ulcerative colitis.PMID 8160776Read ↗

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