Article
Detection of K-ras gene mutation in fecal samples from elderly large intestinal cancer patients and its diagnostic significance.
World journal of gastroenterology - 1 Mar 2004
Wan Jun, Zhang Zi-Qi, You Wei-Di, Sun Hua-Kui, Zhang Jian-Ping, Wang Ya-Hong, Fu Yong-He
Abstract excerpt
AIM: To study the diagnostic significance of K-ras gene mutations in fecal samples from elderly patients with large intestinal cancer. METHODS: DNA was extracted in the fecal and tissue samples from 23 large intestinal cancer patients, 20 colonic adenomatoid polypus patients and 20 healthy subjects. The K-ras gene mutations at the first and second bases of codon 12 were detected by the allele specific mismatch...
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