Article
Identification of subjects at risk for colorectal carcinoma through a test based on K-ras determination in the stool.
Gastroenterology - 1 May 1996
Villa E, Dugani A, Rebecchi A M, Vignoli A, Grottola A, Buttafoco P, Losi L, Perini M, Trande P, Merighi A, Lerose R, Manenti F
Abstract excerpt
BACKGROUND & AIMS: The gold standard for screening for colorectal carcinoma is colonoscopy. The aim of this study was to compare endoscopic results with those obtained using the noninvasive screening test of K-ras determination in the stool in a large population of patients undergoing colonoscopy. METHODS: Two hundred thirty consecutive patients were studied by K-ras amplification on stool-derived DNA using...
Topics
- Adenoma
- Adult
- Aged
- Base Sequence
- Colonoscopy
- Colorectal Neoplasms
- DNA Mutational Analysis
- Feces
- Female
- Gene Amplification
- Genes, ras
