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Article

Villous, hypermucinous mucosa in long standing ulcerative colitis shows high frequency of K-ras mutations.

Gut - 1 Nov 1999

Andersen S N, Lovig T, Clausen O P, Bakka A, Fausa O, Rognum T O

Abstract excerpt

BACKGROUND: K-ras mutation is one of the first genetic alterations in classical colorectal carcinogenesis. AIMS: To investigate the role of K-ras mutations in carcinogenesis, in long standing ulcerative colitis. METHODS: A total of 161 microdissected and 100 DNA samples from 13 patients were analysed for K-ras codons 12 and 13 mutations by means of a combination of enriched polymerase chain reaction amplification...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10517904
DOI: 10.1136/gut.45.5.686
PMCID: PMC1727707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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