Mutant K-ras in apparently normal mucosa of colorectal cancer patients. Its potential as a biomarker of colorectal tumorigenesis.

doi:10.1002/1097-0142(19950315)75:6+<1520::aid-cncr2820751523>3.0.co;2-l

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Article

Mutant K-ras in apparently normal mucosa of colorectal cancer patients. Its potential as a biomarker of colorectal tumorigenesis.

Cancer - 15 Mar 1995

Minamoto T, Yamashita N, Ochiai A, Mai M, Sugimura T, Ronai Z, Esumi H

Abstract excerpt

BACKGROUND: The best way to reduce the incidence of colorectal cancer mortality would be to prevent this cancer. However, none of the biomarkers proposed can accurately identify persons at increased risk of colorectal cancer or those at low risk. As a possible genetic biomarker, K-ras mutations,...

Topics

Adenocarcinoma
Adult
Aged
Biomarkers, Tumor
Colorectal Neoplasms
Female
Genes, ras
Humans
Intestinal Mucosa
Male
Middle Aged
Mutation
Polymerase Chain Reaction

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