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Article

K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias.

Digestion - 1 Jan 2001

Heinzlmann M, Neynaber S, Heldwein W, Folwaczny C

Abstract excerpt

BACKGROUND: The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage fluid from patients with colorectal adenomas and carcinomas. METHODS: In 45 patients with adenomas, 20 patients with colorectal carcinomas and 38 patients with...

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Identifiers

PMID: 11435722
DOI: 10.1159/000051894

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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