Article
Comparative analysis of loss of heterozygosity of specific chromosome 3, 13, 17, and X loci and TP53 mutations in human epithelial ovarian cancer.
Molecular carcinogenesis - 1 Jun 2002
Manderson Emily N, Presneau Nadège, Provencher Diane, Mes-Masson Anne-Marie, Tonin Patricia N
Abstract excerpt
We previously reported the identification of three minimal regions of deletion on the short arm of chromosome 3 (3p) in epithelial ovarian tumor specimens, suggesting that the inactivation of tumor-suppressor genes in these regions may be important in terms of ovarian tumorigenesis. Another previous study of ovarian cancer observed that allele loss of chromosome 179 was frequently found in ovarian tumors that...
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