Genetic alterations of the tumour suppressor gene regions 3p, 11p, 13q, 17p, and 17q in human breast carcinomas.

doi:10.1002/gcc.2870040203

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Article

Genetic alterations of the tumour suppressor gene regions 3p, 11p, 13q, 17p, and 17q in human breast carcinomas.

Genes, chromosomes & cancer - 1 Mar 1992

Andersen T I, Gaustad A, Ottestad L, Farrants G W, Nesland J M, Tveit K M, Børresen A L

Abstract excerpt

Fifty-nine primary breast carcinomas and 11 metastases were examined to identify genetic alterations in the tumour suppressor gene regions 3p, 11p, 13q, 17p, and 17q. Loss of heterozygosity (LOH) was frequently observed on chromosome arms 17p (p144D6 lost in 75%, pYNZ22.1 in 55%, and TP53 in 48%...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Breast Neoplasms
Chromosome Deletion
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 3
Female
Gene Amplification
Genes, Tumor Suppressor
Heterozygote
Humans
Male
Middle Aged
Neoplasm Metastasis

Source

Open in PubMed

Identifiers

PMID: 1373310
DOI: 10.1002/gcc.2870040203

Genes

ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1373310-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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