Article
Allelic loss at chromosomes 3p, 8p, 13q, and 17p associated with poor prognosis in head and neck cancer.
Journal of the National Cancer Institute - 19 Oct 1994
Li X, Lee N K, Ye Y W, Waber P G, Schweitzer C, Cheng Q C, Nisen P D
Abstract excerpt
BACKGROUND: Little is known about the molecular genetic events that contribute to the pathogenesis of squamous cell carcinoma of the upper aerodigestive tract. Previous molecular genetic studies have been limited to the identification of mutations of the p53 (also known as TP53) tumor suppressor gene, activation of a limited set of oncogenes, allelic loss at 3p and other locations, and occasional association with...
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