Chromosome 3p deletions in head and neck carcinomas: statistical ascertainment of allelic loss.

Article

Chromosome 3p deletions in head and neck carcinomas: statistical ascertainment of allelic loss.

Cancer research - 15 Mar 1992

Latif F, Fivash M, Glenn G, Tory K, Orcutt M L, Hampsch K, Delisio J, Lerman M, Cowan J, Beckett M

Abstract excerpt

Loss of function of tumor suppressor genes is important in the origin and progression of common adult tumors. Loss of heterozygosity indicating allelic loss has been used to detect chromosomal regions that harbor these genes. Using over 20 restriction fragment length polymorphism markers spaced t...

Topics

Alleles
Carcinoma, Squamous Cell
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 3
Head and Neck Neoplasms
Heterozygote
Humans
Probability

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