Article
Mapping of chromosome 3p deletions in human epithelial ovarian tumors.
Oncogene - 5 Nov 1998
Lounis H, Mes-Masson A M, Dion F, Bradley W E, Seymour R J, Provencher D, Tonin P N
Abstract excerpt
Epithelial ovarian tumors frequently display deletions on the short arm of chromosome 3 suggesting the existence of tumor suppressor genes within the deleted regions. We have recently established a primary tissue culture system as a model to investigate the genetic events associated with ovarian cancer. The frequencies of loss of heterozygosity (LOH) at 16 loci representative of chromosome 3p in 33 tumor biopsies...
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