Article
Discordance of genetic alterations between primary head and neck tumors and corresponding metastases associated with mutational status of the <i>TP53</i> gene
11 Dec 2001
Abstract excerpt
Ample molecular data are available on the progression from normal mucosa to invasive head and neck squamous cell carcinoma (HNSCC), but information on further genetic progression to metastatic disease is scarce. To obtain insight into the metastatic process, we compared 23 primary HNSCCs with 25 corresponding lymph node metastases (LNMs) and 10 corresponding distant metastases (DMs) with respect to TP53 mutations...
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