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Article

Head and neck tumor sites differ in prevalence and spectrum of <i>p53</i> alterations but these have limited prognostic value

4 May 2004

Abstract excerpt

The tumor site is a strong clinical factor in head and neck squamous cell carcinoma (HNSCC). To clarify the biologic and clinical role of p53 alterations in HNSCC, we have examined the prevalence and the nature of p53 alterations in a large cohort of tumors from the different sites. For immunohistochemical analysis of p53 protein expression, we introduced tyramide signal amplification immunohistochemistry...

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PMID: 15239130
DOI: 10.1002/ijc.11698

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Source receipt: pubmed, retrieved 7 Sept 2026.

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