Article
Genetic alterations between primary head and neck squamous cell carcinoma and recurrence after radiotherapy: recurrence, genetically related cancer, or second primary?
Cancer - 1 Mar 2010
Deganello Alberto, Franchi Alessandro, Sardi Iacopo, Pignataro Lorenzo, Leemans C René, Gallo Oreste
Abstract excerpt
BACKGROUND: In the attempt to characterize the genetic bases of recurrent head and neck squamous cell carcinoma (HNSCC) after radiotherapy (RT), the authors compared the molecular profiles of primary tumors and recurrences. METHODS: TP53 gene status and instability at 10 microsatellite markers we...
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