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Article

Allelic loss in squamous cell carcinomas of the larynx: discordance between primary and metastatic tumors.

Genes, chromosomes & cancer - 1 Oct 1995

Sun P C, el-Mofty S K, Haughey B H, Scholnick S B

Abstract excerpt

The mutational inactivation of suppressor genes, a process required for cancer progression, generates new genetic subclones within a tumor. The allelic losses that frequently unmask these mutations serve not only as markers of the chromosomal locations of these genes but also as clonal fingerprints of the shifting relationships between these genetically heterogeneous cell populations. The rise of the...

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Source

Identifiers

PMID: 8527396
DOI: 10.1002/gcc.2870140209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Allelic loss in squamous cell carcinomas of the larynx: discordance between primary and metastatic tumors.PMID 8527396Read ↗

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