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Article

p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma.

Journal of the National Cancer Institute - 6 Nov 1996

Koch W M, Brennan J A, Zahurak M, Goodman S N, Westra W H, Schwab D, Yoo G H, Lee D J, Forastiere A A, Sidransky D

Abstract excerpt

BACKGROUND: The p53 gene (also known as TP53) may be the most common genetic target involved in the malignant transformation of human cells. Direct sequence analysis has demonstrated that alteration of this gene occurs in approximately 45% of head and neck squamous cell carcinomas. The consequences of p53 mutations in these cancers with respect to tumor behavior and patient survival have not been rigorously...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8901856
DOI: 10.1093/jnci/88.21.1580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma.PMID 8901856Read ↗

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