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Article

A single metal ion plays structural and chemical roles in an aminoacyl-transferase ribozyme.

Biochemistry - 13 Nov 2001

Flynn-Charlebois A, Lee N, Suga H

Abstract excerpt

Catalytically active RNA molecules rely on metal ions for structural and/or catalytic functions. Our in vitro selected aminoacyl-transferase ribozyme is no exception, as it employs a single fully hydrated Mg2+ ion for catalysis [Suga, H., et al. (1998) Biochemistry 37, 10118-10125]. Here we report the essential catalytic residues of the ribozyme and their spatial arrangement in the relation to the metal binding...

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Identifiers

PMID: 11695911
DOI: 10.1021/bi011102k

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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