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Article

Expanded divalent metal-ion tolerance of evolved ligase ribozymes.

Biochimie - 1 Jul 2003

Riley Craig A, Lehman Niles

Abstract excerpt

Class I ligases are artificial ribozymes that catalyze the joining of two single-stranded RNAs. These ribozymes are between 120 and 160 nucleotides in length, making them intermediate in size for catalytic RNAs. Previous characterization of the b1-207 ribozyme suggests that it behaves similar to larger ribozymes in terms of divalent metal-ion dependence. This molecule displays a strong preference for magnesium...

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Identifiers

PMID: 14505824
DOI: 10.1016/s0300-9084(03)00127-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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