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Article

Conservation of helical structure contributes to functional metal ion interactions in the catalytic domain of ribonuclease P RNA.

Journal of molecular biology - 29 Nov 2002

Kaye Nicholas M, Zahler Nathan H, Christian Eric L, Harris Michael E

Abstract excerpt

Like protein enzymes, catalytic RNAs contain conserved structure motifs important for function. A universal feature of the catalytic domain of ribonuclease P RNA is a bulged-helix motif within the P1-P4 helix junction. Here, we show that changes in bulged nucleotide identity and position within h...

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Identifiers

PMID: 12445779
DOI: 10.1016/s0022-2836(02)01094-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12445779-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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