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Article

Mg2+-independent hairpin ribozyme catalysis in hydrated RNA films.

RNA (New York, N.Y.) - 1 Feb 2000

Seyhan A A, Burke J M

Abstract excerpt

The hairpin ribozyme catalyzes RNA cleavage in partially hydrated RNA films in the absence of added divalent cations. This reaction exhibits the characteristics associated with the RNA cleavage reaction observed under standard conditions in solution. Catalysis is a site-specific intramolecular transesterification reaction, requires the 2'-hydroxyl group of substrate nucleotide A(-1), and generates 2',3'-cyclic...

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Identifiers

PMID: 10688358
DOI: 10.1017/s1355838200991441
PMCID: PMC1369905

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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