Effects of stratification in the analysis of affected-sib-pair data: benefits and costs.

Abstract excerpt

The benefits and costs of stratification of affected-sib-pair (ASP) data were examined in three situations: (1) when there is no difference in identity-by-descent (IBD) allele sharing between stratified and unstratified ASP data sets; (2) when there is an increase in IBD allele sharing in one of the stratified groups; and (3) when the data are stratified on the basis of IBD allele-sharing status at one locus, and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Age of Onset
• Share to Alleles
• Share to Chromosome Mapping