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Article

Commentary: the affected sib-pair method in the context of an epidemiologic study design.

Genetic epidemiology - 1 Jan 1991

Khoury M J, Flanders W D, Lipton R B, Dorman J S

Abstract excerpt

The purpose of this commentary is to provide a framework for using the well-known sib-pair methodology in the context of epidemiologic study designs. Using examples from the Pittsburgh family studies of insulin-dependent diabetes mellitus, we illustrate that the sib-pair method can be used in family-based epidemiologic studies. In a cohort study, unaffected relatives of probands ascertained from well-defined...

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PMID: 1756950
DOI: 10.1002/gepi.1370080408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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