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Article

Spatiotemporal progression of neurodegeneration and glia activation in the wobbler neuropathy of the mouse.

Neuroreport - 8 Nov 1999

Rathke-Hartlieb S, Schmidt V C, Jockusch H, Schmitt-John T, Bartsch J W

Abstract excerpt

The wobbler mouse (phenotype WR; genotype wr/wr) has been investigated as a model for neurodegenerative diseases like SMA and ALS. A new diagnostic marker based on a polymorphism in the closely linked chaperonine gene Cct4 enabled us to diagnose the allelic status at the wr locus within the original background strain C57BL/6. Using this marker, we investigated the spatiotemporal progression of neuropathology in...

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Identifiers

PMID: 10599854
DOI: 10.1097/00001756-199911080-00028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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