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Article

Genetic modifiers that aggravate the neurological phenotype of the wobbler mouse.

Neuroreport - 25 Mar 2002

Ulbrich Michael, Schmidt Volker C, Ronsiek Melanie, Mussmann Anke, Bartsch Jörg W, Augustin Martin, Jockusch Harald, Schmitt-John Thomas

Abstract excerpt

The autosomal recessive mutation wobbler of the mouse (phenotype WR; genotype wr/wr) causes muscular atrophy due to motoneuron degeneration with 100% penetrance on the standard Mus musculus laboratorius C57BL/6J background. In inter- and backcrosses with M. m. castaneus strain CAST/EI we have observed a variability in the severity of neurological symptoms. Approximately 15% of the WR (wr/wr) CAST/B6 hybrids were...

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PMID: 11930176
DOI: 10.1097/00001756-200203250-00035

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CAST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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