Article
The Spatiotemporal Pattern of Degeneration in the Cerebellum of the Wobbler Mouse.
Journal of neuropathology and experimental neurology - 1 Apr 2016
Saberi Darius, Ott Bastian, Dahlke Carolin, Matschke Veronika, Schmitt-John Thomas, Theiss Carsten
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a common neurodegenerative disease that affects motor neurons in the spinal cord and motor cortex. Various mouse models have been used to investigate the progression of the pathology of sporadic and familial ALS. Degeneration in the spinal cord and motor cortex in the Wobbler mouse model of sporadic ALS have been documented, but alterations of the cerebellum during disease...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
