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Article

Mutations of p53 in morphologically non-neoplastic mucosa of long-standing ulcerative colitis.

Japanese journal of cancer research : Gann - 1 Feb 2001

Takaku H, Ajioka Y, Watanabe H, Hashidate H, Yamada S, Yokoyama J, Kazama S, Suda T, Hatakeyama K

Abstract excerpt

Two cases of ulcerative colitis (UC)-associated carcinoma or dysplasia and morphologically non-neoplastic mucosa with p53 protein overexpression (MNNM-p53OE) were selected. DNA was extracted from the paraffin blocks of these lesions and exons 5 - 8 of the p53 gene were analyzed by PCR and direct sequencing. In addition, mutations in K-ras codon 12 were analyzed by PCR-RFLP methods. MNNM-p53OE was located...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11223540
DOI: 10.1111/j.1349-7006.2001.tb01073.x
PMCID: PMC5926702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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