Article
High frequency of K-ras mutations in human colorectal hyperplastic polyps.
Gut - 1 May 1997
Otori K, Oda Y, Sugiyama K, Hasebe T, Mukai K, Fujii T, Tajiri H, Yoshida S, Fukushima S, Esumi H
Abstract excerpt
BACKGROUND: Hyperplastic polyps are common benign colorectal polyps, and are thought to have little association with malignant tumours in the colorectum. However, several reports suggest that some hyperplastic polyps may develop into colorectal neoplasms. AIM: To clarify genetic alterations in co...
Topics
- Adenoma
- Aged
- Aged, 80 and over
- Colonic Diseases
- Colorectal Neoplasms
- Female
- Genes, ras
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Mutation
- Polymorphism, Restriction Fragment Length