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Article

K-ras gene mutations in normal colorectal tissues from K-ras mutation-positive colorectal cancer patients.

Cancer research - 15 Jun 1997

Zhu D, Keohavong P, Finkelstein S D, Swalsky P, Bakker A, Weissfeld J, Srivastava S, Whiteside T L

Abstract excerpt

K-ras gene mutations have been reported as early events in colorectal tumorigenesis, but their role in tumor initiation and development is still unclear. To analyze and compare K-ras mutational patterns between colorectal tissues at different stages of tumor progression in individual patients, 65 colorectal tissue samples, including carcinoma, adenoma, histologically normal mucosa, submucosal muscularis propria,...

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PMID: 9192830

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