K-ras gene mutations in normal colorectal tissues from K-ras mutation-positive colorectal cancer patients.

Article

K-ras gene mutations in normal colorectal tissues from K-ras mutation-positive colorectal cancer patients.

Cancer research - 15 Jun 1997

Zhu D, Keohavong P, Finkelstein S D, Swalsky P, Bakker A, Weissfeld J, Srivastava S, Whiteside T L

Abstract excerpt

K-ras gene mutations have been reported as early events in colorectal tumorigenesis, but their role in tumor initiation and development is still unclear. To analyze and compare K-ras mutational patterns between colorectal tissues at different stages of tumor progression in individual patients, 65...

Topics

Adenoma
Adult
Aged
Aged, 80 and over
Biopsy
Colon
Colorectal Neoplasms
Electrophoresis
Female
Genes, ras
Humans
Intestinal Mucosa
Male
Middle Aged
Mutation
Rectum

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