Article
Microsatellite instability in long-standing ulcerative colitis.
Scandinavian journal of gastroenterology - 1 May 2007
Løvig Tone, Andersen Solveig Norheim, Clausen Ole Petter, Rognum Torleiv Ole
Abstract excerpt
OBJECTIVE: Ulcerative colitis (UC) is a chronic inflammatory disease of the colon associated with a high risk of developing colorectal cancer. Several genetic alterations have been documented in dysplasia and cancer developing in UC. Concerning microsatellite instability (MSI), many contradictory results have been published. We therefore analysed a large, well-characterized UC material for MSI to elucidate its...
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