Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic analysis of rolled, which encodes a Drosophila mitogen-activated protein kinase.

Genetics - 1 Oct 1999

Lim Y M, Nishizawa K, Nishi Y, Tsuda L, Inoue Y H, Nishida Y

Abstract excerpt

Genetic and molecular characterization of the dominant suppressors of D-raf(C110) on the second chromosome identified two gain-of-function alleles of rolled (rl), which encodes a mitogen-activated protein (MAP) kinase in Drosophila. One of the alleles, rl(Su23), was found to bear the same molecular lesion as rl(Sem), which has been reported to be dominant female sterile. However, rl(Su23) and the current stock of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium-Calmodulin-Dependent Protein Kinases
Share to Extracellular Signal-Regulated MAP Kinases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Infertility, Female

Share to Microscopy, Electron, Scanning

Share to Mitogen-Activated Protein Kinases

Share to Proto-Oncogene Proteins c-raf

Share to Suppression, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 10511556
DOI: 10.1093/genetics/153.2.763
PMCID: PMC1460789

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic analysis of rolled, which encodes a Drosophila mitogen-activated protein kinase.PMID 10511556Read ↗

A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways.Semantic proximity Read ↗

A genetic screen for modifiers of drosophila Src42A identifies mutations in Egfr, rolled and a novel signaling gene.Semantic proximity Read ↗

Drosophila gain-of-function mutant RTK torso triggers ectopic Dpp and STAT signaling.Semantic proximity Read ↗

Dominant mutations of Drosophila MAP kinase kinase and their activities in Drosophila and yeast MAP kinase cascades.Semantic proximity Read ↗

A screen for mutations that prevent lethality caused by expression of activated sevenless and Ras1 in the Drosophila embryo.Semantic proximity Read ↗

Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates.Semantic proximity Read ↗

Genetic and molecular analyses of mutations involved in Drosophila raf signal transduction.Semantic proximity Read ↗

A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans.Semantic proximity Read ↗

Targeted expression of the class II phosphoinositide 3-kinase in Drosophila melanogaster reveals lipid kinase-dependent effects on patterning and interactions with receptor signaling pathways.Semantic proximity Read ↗

A genetic screen for modifiers of a kinase suppressor of Ras-dependent rough eye phenotype in Drosophila.Semantic proximity Read ↗

Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.Semantic proximity Read ↗

Identification of autosomal regions involved in Drosophila Raf function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.