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Article

Genetic and molecular analyses of mutations involved in Drosophila raf signal transduction.

The EMBO journal - 1 Jun 1994

Lu X, Melnick M B, Hsu J C, Perrimon N

Abstract excerpt

We have identified dominant mutations that suppress the lethality associated with an R217-->L mutation in the GTP.Ras binding region (CR1) of the Drosophila raf (D-raf) serine/threonine kinase. Four intragenic and seven extragenic suppressors were recovered. Each of the four intragenic mutations contains one compensatory amino acid change located in either the CR1 or the kinase domain of D-raf. The seven...

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Source

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Identifiers

PMID: 8013459
DOI: 10.1002/j.1460-2075.1994.tb06549.x
PMCID: PMC395133

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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