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Article

Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.

Genetics - 1 Mar 1995

Sekelsky J J, Newfeld S J, Raftery L A, Chartoff E H, Gelbart W M

Abstract excerpt

The decapentaplegic (dpp) gene of Drosophila melanogaster encodes a growth factor that belongs to the transforming growth factor-beta (TGF-beta) superfamily and that plays a central role in multiple cell-cell signaling events throughout development. Through genetic screens we are seeking to identify other functions that act upstream, downstream or in concert with dpp to mediate its signaling role. We report here...

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Identifiers

PMID: 7768443
DOI: 10.1093/genetics/139.3.1347
PMCID: PMC1206461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.PMID 7768443Read ↗

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Identification of chromosomal regions involved in decapentaplegic function in Drosophila.Semantic proximity Read ↗

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MADR1, a MAD-related protein that functions in BMP2 signaling pathways.Semantic proximity Read ↗

The Drosophila Medea gene is required downstream of dpp and encodes a functional homolog of human Smad4.Semantic proximity Read ↗

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A genetic screen for maternal-effect suppressors of decapentaplegic identifies the eukaryotic translation initiation factor 4A in Drosophila.Semantic proximity Read ↗

An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo.Semantic proximity Read ↗

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