Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of autosomal regions involved in Drosophila Raf function.

Genetics - 1 Oct 2000

Li W, Noll E, Perrimon N

Abstract excerpt

Raf is an essential downstream effector of activated p21(Ras) (Ras) in transducing proliferation or differentiation signals. Following binding to Ras, Raf is translocated to the plasma membrane, where it is activated by a yet unidentified "Raf activator." In an attempt to identify the Raf activator or additional molecules involved in the Raf signaling pathway, we conducted a genetic screen to identify genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crosses, Genetic
Share to Drosophila melanogaster
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Gene Expression Regulation, Developmental

Share to Mutagenesis

Share to Proto-Oncogene Proteins c-raf

Source

Open in PubMed Open full text

Identifiers

PMID: 11014822
DOI: 10.1093/genetics/156.2.763
PMCID: PMC1461272

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of autosomal regions involved in Drosophila Raf function.PMID 11014822Read ↗

Developmental and molecular characterization of mutations in the Drosophila-raf serine/threonine protein kinase.Semantic proximity Read ↗

Drosophila gain-of-function mutant RTK torso triggers ectopic Dpp and STAT signaling.Semantic proximity Read ↗

A genetic screen for modifiers of drosophila Src42A identifies mutations in Egfr, rolled and a novel signaling gene.Semantic proximity Read ↗

Ras1 interacts with multiple new signaling and cytoskeletal loci in Drosophila eggshell patterning and morphogenesis.Semantic proximity Read ↗

The Drosophila retained/dead ringer gene and ARID gene family function during development.Semantic proximity Read ↗

Identification of genomic regions that interact with a viable allele of the Drosophila protein tyrosine phosphatase corkscrew.Semantic proximity Read ↗

A second-site noncomplementation screen for modifiers of Rho1 signaling during imaginal disc morphogenesis in Drosophila.Semantic proximity Read ↗

A lin-45 raf enhancer screen identifies eor-1, eor-2 and unusual alleles of Ras pathway genes in Caenorhabditis elegans.Semantic proximity Read ↗

Genome-Wide Screen for New Components of the Drosophila melanogaster Torso Receptor Tyrosine Kinase Pathway.Semantic proximity Read ↗

A cytogenetic analysis of chromosomal region 31 of Drosophila melanogaster.Semantic proximity Read ↗

E2F-dependent transcription of the raf proto-oncogene during Drosophila development.Semantic proximity Read ↗

Genetic and bioinformatic analysis of 41C and the 2R heterochromatin of Drosophila melanogaster: a window on the heterochromatin-euchromatin junction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.