Article
A genetic screen for modifiers of a kinase suppressor of Ras-dependent rough eye phenotype in Drosophila.
Genetics - 1 Nov 2000
Therrien M, Morrison D K, Wong A M, Rubin G M
Abstract excerpt
kinase suppressor of Ras (ksr) encodes a putative protein kinase that by genetic criteria appears to function downstream of RAS in multiple receptor tyrosine kinase (RTK) pathways. While biochemical evidence suggests that the role of KSR is closely linked to the signal transduction mechanism of the MAPK cascade, the precise molecular function of KSR remains unresolved. To further elucidate the role of KSR and to...
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