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Article

p53 mutations in british patients with hepatocellular carcinoma: clustering in genetic hemochromatosis.

Gastroenterology - 1 Jul 1999

Vautier G, Bomford A B, Portmann B C, Metivier E, Williams R, Ryder S D

Abstract excerpt

BACKGROUND & AIMS: Environmental factors are important in the etiology of hepatocellular carcinoma (HCC). Aflatoxin B1 causes a specific point mutation in the p53 tumor-suppressor gene in exposed individuals. In Western populations, mutations of this gene seem to be less frequent. We have investigated the role of p53 mutations in tumorigenesis in British patients with HCC. The aim of this study was to determine...

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Identifiers

PMID: 10381922
DOI: 10.1016/s0016-5085(99)70562-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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