Article
p53 gene mutations and 17p allelic deletions in hepatocellular carcinoma from Japan.
Cancer - 15 Jul 1993
Nose H, Imazeki F, Ohto M, Omata M
Abstract excerpt
BACKGROUND: p53 gene mutations at codon 249 have been reported in hepatocellular carcinoma (HCC) from China and South Africa, a phenomenon shown to be closely associated with food contamination by aflatoxin. There have been few reports, however, in regard to p53 gene mutations in HCC from other g...
Topics
- Alleles
- Base Sequence
- Carcinoma, Hepatocellular
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- Female
- Genes, p53
- Humans
- Japan
- Liver Neoplasms
- Male
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length