Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of aflatoxin induced p53 mutation at codon 249 (R249s) in hepatocellular carcinoma patients with and without hepatitis B surface antigen (HBsAg).

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Chittmittrapap Salyavit, Chieochansin Thaweesak, Chaiteerakij Roongruedee, Treeprasertsuk Sombat, Klaikaew Naruemon, Tangkijvanich Pisit, Komolmit Piyawat, Poovorawan Yong

Abstract excerpt

BACKGROUND: A missense mutation in exon 7 (R249S) of the p53 tumor suppressor gene is characteristic of aflatoxin B1 (AFB1) exposure. AFB1 is believed to have a synergistic effect on hepatitis virus B (HBV) carcinogenesis. However, results of studies comparing R249S prevalence among patients are conflicting. The aim of this study was to determine the prevalence of the R249S mutation in hepatocellular carcinoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aflatoxins
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

Share to Hepatitis B Surface Antigens

Share to Hepatitis B virus

Share to Liver Neoplasms

Share to Neoplasm Staging

Share to Serologic Tests

Source

Identifiers

PMID: 24460352
DOI: 10.7314/apjcp.2013.14.12.7675

Genes

AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of aflatoxin induced p53 mutation at codon 249 (R249s) in hepatocellular carcinoma patients with and without hepatitis B surface antigen (HBsAg).PMID 24460352Read ↗

The aflatoxin-induced TP53 mutation at codon 249 (R249S): biomarker of exposure, early detection and target for therapy.Semantic proximity Read ↗

Genome-wide association study of the TP53 R249S mutation in hepatocellular carcinoma with aflatoxin B1 exposure and infection with hepatitis B virusSemantic proximity Read ↗

P53 tumor suppressor gene mutations in hepatocellular carcinoma patients in India.Semantic proximity Read ↗

The p53 mutation spectrum in hepatocellular carcinoma from Guangxi, China : role of chronic hepatitis B virus infection and aflatoxin B1 exposure.Semantic proximity Read ↗

Low Frequency of Aflatoxin Induced TP53 Gene Codon 249 Mutation in Hepatocellular Carcinoma from Egyptian Patients Living in the Nile Delta Region.Semantic proximity Read ↗

High prevalence of mutations at codon 249 of the p53 gene in hepatocellular carcinomas from Senegal.Semantic proximity Read ↗

P53 mutations in hepatocellular carcinoma patients in Egypt.Semantic proximity Read ↗

Association between TP53 R249S mutation and polymorphisms in TP53 intron 1 in hepatocellular carcinoma.Semantic proximity Read ↗

p53 mutation in hepatocellular carcinoma after aflatoxin exposure.Semantic proximity Read ↗

p53 mutations and aflatoxin B1 exposure in hepatocellular carcinoma patients from Thailand.Semantic proximity Read ↗

The prevalence of the mutation in codon 249 of the P53 gene in patients with hepatocellular carcinoma (HCC) in Turkey.Semantic proximity Read ↗

P53 codon 249 mutation in hepatocellular carcinomas from Nigeria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.