Mutations of the tumour suppressor gene p53 in colorectal and hepatocellular carcinomas.

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Article

Mutations of the tumour suppressor gene p53 in colorectal and hepatocellular carcinomas.

Annals of the Academy of Medicine, Singapore - 1 Mar 1995

Shi C Y, Phang T W, Wee A, Ngoi S S, Lin Y, Li B, Ong C N, Lee H P

Abstract excerpt

The present study describes mutations of the tumour suppressor gene p53 in a local collection of colorectal and hepatocellular carcinomas (HCCs). Tumour DNA was extracted from both fresh and paraffin-embedded tissues and exons 5-8 of the p53 gene were amplified by polymerase chain reaction (PCR)....

Topics

Adenocarcinoma
Biomarkers, Tumor
Carcinoma, Hepatocellular
Colorectal Neoplasms
DNA Mutational Analysis
DNA, Neoplasm
Female
Genes, p53
Humans
Incidence
Liver Neoplasms
Male
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Singapore

Source

Open in PubMed

Identifiers

PMID: 7653961

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7653961-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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