Article

CTCF mediates the cis-regulatory hubs in mouse hearts

2022-11-05

Abstract excerpt

<h4>ABSTRACT</h4> The 3D chromatin architecture establishes a complex network of genes and regulatory elements necessary for transcriptomic regulation in development and disease. This network can be modelled by cis-regulatory hubs (CRH), which underscore the local functional interactions between enhancers and promoter regions and differ from other higher-order chromatin structures such as topologically associated...

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Literature Corpus work: fed1a7d2-2b64-5b1f-859f-d2a13a7b0091
DOI: 10.1101/2022.11.04.515249

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