Article

Systematic analysis of transcription factor combinatorial binding uncovers TEAD1 as an antagonist of tissue-specific transcription factors in human organogenesis

2023-10-07

Abstract excerpt

<h4>ABSTRACT</h4> Gene expression is largely controlled by transcription factors (TFs), which bind to enhancers in combination with other TFs in a mechanism known as combinatorial binding. While combinatorial binding is well established, a comprehensive view of tissue-specific TF combinations at active enhancers during human embryonic development is still lacking. Using a two-step pipeline to detect co-occurring...

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Literature Corpus work: 33d4d09c-b51b-5b32-becd-650f9a90d70c
DOI: 10.1101/2023.10.05.561094

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Systematic analysis of transcription factor combinatorial binding uncovers TEAD1 as an antagonist of tissue-specific transcription factors in human organogenesisDOI 10.1101/2023.10.05.561094Read

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