Article

Polygenic coronary artery disease association with brain atrophy in the cognitively impaired

2022-02-13

Abstract excerpt

<h4>ABSTRACT</h4> The role cardiac function plays in the predilection for, and progression of, Alzheimer’s disease (AD), is complex and unclear. While a number of low-frequency genetic variants of large effect-size have been shown to underlie both cardiovascular disease and dementia, recent studies have highlighted the importance of common genetic variants of small-effect size, which, in aggregate, are embodied by...

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Literature Corpus work: fdf8db4d-2a15-506c-8c8b-cb585e279f31
DOI: 10.1101/2022.02.11.22270852

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