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Polygenic Risk Score Modifies Risk of Coronary Artery Disease Conferred by Low-Density Lipoprotein Cholesterol

2020-03-06

Abstract excerpt

<h4>Background</h4> An individual’s lifetime risk of Coronary Artery Disease (CAD) is determined by a combination of genetic and lifestyle factors. Whilst adherence to a healthy lifestyle can help individuals with high genetic risk reduce their lifetime risk of CAD, the extent to which blood lipid levels affect CAD risk in individuals with varying genetic risk remains unknown. To explore how genetics, blood lipids...

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Literature Corpus work
a6129660-844f-5efb-a419-56073cdde893
DOI
10.1101/2020.03.01.20029454
Open publication

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Polygenic Risk Score Modifies Risk of Coronary Artery Disease Conferred by Low-Density Lipoprotein CholesterolDOI 10.1101/2020.03.01.20029454
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