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Polygenic risk and incident coronary heart disease in a large multiethnic cohort

28 Mar 2024

Abstract excerpt

Many studies support the notion that polygenic risk scores (PRS) improve risk prediction for coronary heart disease (CHD) beyond conventional risk factors. However, PRS are not yet considered risk-enhancing factor in guidelines. Our objective was to determine the predictive performance of a commercially available PRS (CARDIO inCode-Score®) compared with the Pooled Cohorts Equations (PCE) in a contemporary,...

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PMID: 38601895
DOI: 10.1016/j.ajpc.2024.100661

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