Article

Modulation of Nur77-DNA Interactions by the Glucocorticoid Receptor

2025-10-28

Abstract excerpt

Nuclear receptors (NRs) comprise a superfamily of (ligand-)regulated transcription factors that are pivotal in orchestrating gene networks essential for development, metabolism, and cellular homeostasis. Their activity is critical for normal physiology, and consequently, dysregulation of NR signaling is implicated in a wide array of human diseases. Within this superfamily, the orphan nuclear receptor Nur77 and the...

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Literature Corpus work: fd12908f-25e7-58b6-8178-ad2188caa28e
DOI: 10.1101/2025.10.28.685035

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