Article
The human glucocorticoid receptor: molecular basis of biologic function.
Steroids - 1 Jan 2010
Nicolaides Nicolas C, Galata Zoi, Kino Tomoshige, Chrousos George P, Charmandari Evangelia
Abstract excerpt
The characterization of the subfamily of steroid hormone receptors has enhanced our understanding of how a set of hormonally derived lipophilic ligands controls cellular and molecular functions to influence development and help achieve homeostasis. The glucocorticoid receptor (GR), the first member of this subfamily, is a ubiquitously expressed intracellular protein, which functions as a ligand-dependent...
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