Article

From 2D to 4D: a Containerized Workflow and Browser to Explore Dynamic Chromatin Architecture

2025-07-18

Abstract excerpt

Characterizing the physical organization of the genome is essential for understanding long-range gene regulation, chromatin compartmentalization, and epigenetic accessibility. Hi-C experiments generate two-dimensional (2D) genome-wide contact maps of chromatin interactions by capturing the spatial proximity between genomic loci, which reveal interaction frequencies but lack the spatial resolution needed to interpr...

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Literature Corpus work: fc431383-1257-515c-9f68-834101f6fc1d
DOI: 10.1101/2025.07.13.664622

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