Article

Sequence-based modeling of genome 3D architecture from kilobase to chromosome-scale

2021-05-20

Abstract excerpt

The structural organization of the genome plays an important role in multiple aspects of genome function. Understanding how genomic sequence influences 3D organization can help elucidate their roles in various processes in healthy and disease states. However, the sequence determinants of genome structure across multiple spatial scales are still not well understood. To learn the complex sequence dependencies of mul...

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Literature Corpus work: 5bc960d5-2b69-5c33-85b2-71c03007fa6d
DOI: 10.1101/2021.05.19.444847

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